Aims The aim of this systematic review was to assess the published clinical evidence
on interactions between herbal and conventional drugs.
Methods Four electronic databases were searched for case reports, case series or clinical
trials of such interactions. The data were extracted and validated using a scoring system
for interaction probability.
Medicinal plant use plays an important role in the healthcare of many South Africans. Furthermore, in orthodox
medicine, conventional antimicrobial agents are amongst themost commonly prescribed groups of drugs. Therefore,
due to the prevalence of use of these two forms of healthcare, there is a high probability for their concurrent